Background and Research Areas

Hypertension is a major risk factor for adverse cardiovascular events such as myocardial infarction and stroke.

Hypertension is very common in the US and the prevalence is increasing steadily in black and white men and women, Figure 1, due in large part to the increase in proportion of overweight and obese individuals in the population.

Hypertension is a multifactorial disease with local vascular endothelial dysfunction, imbalances in circulating and local hormones, alterations in renal function, changes in cardiac and neural control of the circulation, genetic background and environment all contributing.

Thus, there are many potential causes of hypertension and here at the University of Florida there are a number of research groups investigating different aspects of hypertension, many of whom are collaborating on basic, clinical and translational research projects.

Given below are the primary focus areas of investigation by members of the University of Florida Hypertension Center:

Research Areas:

Aging:
Chris Baylis
Christy Carter
Christiaan Leeuwenburgh
Nihal Tumer
Philip Scarpace
Marian Limacher

Endothelial Dysfunction, Oxidative Stress, Inflammation and Repair:
Chris Baylis
Alex Lucas
Mark Segal
Carl Pepine
Kirk Conrad
Christiaan Leeuwenburgh

Neural Control/ Stress:
Maureen Keller-Wood
Mohan Raizada
Neil Rowland
Philip Scarpace
Debbie Scheuer
Colin Sumners
Nihal Tumer
Charles Wood
Linda Hayward

Hypertension in Chronic Kidney Disease:
Chris Baylis
Brian Cain
Mark Segal
David Weiner
Charles Wingo

Obesity/ Metabolic Syndrome:
Christy Carter
Nihal Tumer
Philip Scarpace
Yuri Sautin
Rhonda DeHoff
Marian Limacher
Neil Rowland

Renin-Angiotensin-Aldosterone System:
Brian Cain
Michael Katovich
Mohan Raizada
Peter Sayeski
Colin Sumners
David Weiner
Charles Wingo

Gene Therapy for Cardiovascular Disease:
Barry Byrne
Michael Katovich
Mohan Raizada
Colin Sumners
Glenn Walter

The Kidney as Cause of Hypertension:
Chris Baylis
Brian Cain
Michelle Gumz
David Weiner
Charles Wingo

Hypertension in Pregnancy:
Chris Baylis
Kirk Conrad
Maureen Keller-Wood
Charles Wood

Fetal Programming of Hypertension:
Linda Hayward
Kirk Conrad
Debbie Scheuer
Maureen Keller-Wood
Charles Wood

The Heart in Hypertension:
Carl Pepine
Hideko Kasahara
Linda Hayward
Julie Johnson
Rhonda DeHoff
David Gilland
Marian Limacher
Alex Lucas

Cardiovascular Development and Hypertension:
Paul Oh
Hideko Kasahara

Exercise and Cardiovascular Disease:
Brad Behnke
Glenn Walter

Pharmacotherapy and Pharmacogenomics:
Julie Johnson
Rhonda DeHoff